GENEVA, Switzerland — The World Health Organization (WHO) has clarified that there is no conclusive scientific evidence linking the use of paracetamol during pregnancy to autism-related issues.
The global health body stated that large-scale studies conducted over the past decade have explored the possible associations but have not been able to establish a consistent link.
The WHO’s statement aimed to provide reassurance on the matter. “Extensive research has been undertaken over the past decade, including large-scale studies, looking into links between acetaminophen use during pregnancy and autism. At this time, no consistent association has been established,” the organization said.
While the WHO urged expectant mothers to continue following the advice of their doctors, it also noted that all medicines should be used with caution during pregnancy, especially in the first trimester.
Clarifying the science on autism and vaccines
The WHO’s clarification comes amid ongoing public interest in the causes of autism. The organization indicated that nearly 62 million people, or about 1 in 127 globally, live with autism.
“Although awareness and diagnosis have improved in recent years, the exact causes of autism have not been established, and it is understood there are multiple factors that can be involved,” the WHO stated.
The global health body also took the opportunity to reaffirm its long-standing position that childhood vaccines do not cause autism. It pointed out that large, high-quality studies from many countries have all reached the same conclusion.
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“Original studies suggesting a link were flawed and have been discredited. Since 1999, independent experts advising WHO have repeatedly confirmed that vaccines, including those with thiomersal or aluminum, do not cause autism or other developmental disorders.
“Childhood vaccine schedules are developed through a careful, extensive and evidence-based process involving global experts and country input. The childhood immunization schedule, carefully guided by WHO, has been adopted by all countries, and has saved at least 154 million lives over the past 50 years,” the statement added.
The WHO concluded with a warning that delaying or disrupting vaccination programs increases the risk of infections for children and the wider community, particularly for infants too young to be vaccinated and individuals with weakened immune systems.

